How much progesterone is safe?

How Much Progesterone is Safe?

*How Much Progesterone is Too Much? 

While a very few websites are recommending ultra-high doses of progesterone daily, there is no scientific basis for using this extreme amount (100-500 mg/daily).

Following, is a quote from a website selling a progesterone (Chinese) cream:

For general use and to reverse mild symptoms 100-200mg/day progesterone is needed. If severe problems are experienced 400-500mg/day are needed.

This is bad advice.

The Key Principle

Supplementing with a hormone is not the same as supplementing, for example, with Vitamin C, where at times, more is better.  This principle of “more is better” does NOT apply to hormone supplementation.

Being seduced by this excessive quantity of progesterone daily (100-500 mg), is risky!  Why?  It does not parallel your body’s natural hormone cycles and will, in time, result in acute hormone imbalances and a desensitization of progesterone receptors, leading to acute “estrogen dominance” and all of the subsequent unpleasant symptoms, not the least of which, is an increased risk for female-specific cancers.

It does, however, enrich the sales of the company making these unfounded claims.

Rather than supplement with ultra-high doses of progesterone, in a desperate attempt to balance high levels of estrogensreduce the influx of environmental estrogens & successfully manage stress, while paralleling your body’s normal progesterone production.  This is safely accomplished with an optimally formulated progesterone cream, (free of Chinese progesterone).

This long-standing, common-sense approach to hormonal imbalances works in harmony with your natural biology.  And, it does so, safely!


All the science and all the clinical experience of the past 45+ years, demonstrate that paralleling your body’s normal progesterone productionwhile avoiding environmental estrogens, will allow you achieve the best of health, safely & naturally.

See also, Overview